Are you a grid lover? It's a design basic that so many do not use when planning out their site. The grid has long been an invaluable tool for creating order out of chaos for designers of all kinds—from city planners to architects to typesetters and graphic artists. In recent years, web designers, too, have come to discover the remarkable power that grid-based design can afford in creating intuitive, immersive, and beautiful user experiences.
So if you answered yes to my question then you must get Ordering Disorder: Grid Principles for Web Design. This great book delivers a definitive take on grids and the Web. It provides both the big ideas and the brass-tacks techniques of grid-based design.
If you prefer some online source, here are some of my favorite grid resources